Brodeur has spent the past two decades of her professional life in the literary world, discovering voices, cultivating talent, and working to amplify underrepresented writers. Her publishing career began with founding the fiction magazine, Zoetrope: All-Story, with filmmaker Francis Ford Coppola, where she served as editor in chief from 1996-2002. The magazine has won the prestigious National Magazine Award for best fiction four times. In 2005, she became an editor at Harcourt (later, HMH Books), where she acquired and edited literary fiction and memoir. Adrienne left publishing in 2013 to become Creative Director — and later Executive Director — of Aspen Words, a literary arts nonprofit and program of the Aspen Institute. In 2017, she launched the Aspen Words Literary Prize, a $35,000 annual award for an influential work of fiction that illuminates a vital contemporary issue and demonstrates the transformative power of literature on thought and culture.
She splits her time between Cambridge and Cape Cod, where she lives with her husband and children.